Which organism is known to cause rapidly progressive erythema and tenderness in wound edges post-operatively?

The organism that is known to cause rapidly progressive erythema and tenderness in wound edges post-operatively is Group B streptococcus. This organism can lead to a serious infection characterized by quick-onset redness, swelling, and tenderness around surgical wounds. The presence of these symptoms can indicate an invasive bacterial infection, and Group B strep is particularly notable for its aggressiveness in such scenarios.

While Staphylococcus aureus is also a common cause of post-operative infections, it typically presents with localized abscess formation and may not always be as rapid or severe in progression compared to infections caused by Group B streptococcus.

Escherichia coli is predominantly linked to abdominal and urinary tract infections and is less commonly associated with rapid erythema in wound healing scenarios.

Clostridium perfringens, known for causing gas gangrene, can also cause significant tissue destruction, but its clinical presentation would typically involve gas production and necrosis rather than the erythema and tenderness described.

Thus, the rapid progression of symptoms associated with Group B streptococcus makes it the most fitting choice for this particular question regarding post-operative wound infections.